Description
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Dedication -
Contributors -
Preface -
Chapter 1: Anticancer Drug Development: An Introduction -
Chapter 2: Alkylating Agents -
Chapter 3: Antimetabolites: Hydroxyurea, Pyrimidine and Purine Analogs, and L-Asparaginase -
Chapter 4: Antimetabolites: Antifolates -
Chapter 5: Antimitotics -
Chapter 6: DNA Repair, Apoptotic Pathways, CDK Inhibitors -
Chapter 7: Epigenetic Modulators -
Chapter 8: Differentiating Agents and Microenvironment -
Chapter 9: Hormonal Therapies Alone and in Combinations for Treatment of Breast Cancer -
Chapter 10: Male Hormonal Therapies -
Chapter 11: Targeted Therapies (Small Molecules) -
Chapter 12: Monoclonal Antibodies Including Immunoconjugates and Cytokine-Directed Agents -
Chapter 13: Immunotherapeutics Including Vaccines, Bispecifics, CAR-T, and Checkpoint Inhibitors -
Chapter 14: Multiple Myeloma as a Paradigm for Multi-Targeted Intervention -
Chapter 15: Transplant-Related Agents -
Chapter 16: Basic Drug Development With Structural Considerations -
Chapter 17: Integral Components in Development of Clinical Trials: PK/PD, Statistics, and Principles of Rational Combinatorial Therapies -
Chapter 18: Drug Approval and Regulatory Issues
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